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The oral dosage formulation herein described provides a preferred release period suitable for the dosing of clonidine twice per day, at twelve hour intervals.
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Such an intense program bestows a sense of responsibility upon participants, compelling and motivating them to maintain their sobriety and meet the standards of outpatient therapy.
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The second was infected as well but a saline solution was added (placebo), and the third one was a negatice control (saline solution only)
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